纳米材料
纳米技术
纳米医学
药物输送
纳米载体
材料科学
量子点
介孔二氧化硅
纳米颗粒
表面改性
生物相容性
胶体金
介孔材料
化学
有机化学
物理化学
催化作用
冶金
作者
Keyvan Nasirzadeh,Shahram Nazarian,Seyed Mohammad Gheibi Hayat
出处
期刊:Journal of Applied Biotechnology Reports
[Armenian Green Publishing Co.]
日期:2016-12-06
卷期号:3 (2): 395-402
被引量:12
摘要
Recent investigations have been shown that inorganic nanomaterials including gold nanoparticles, nonporous and mesoporous silica nanoparticles, magneticnanoparticles, and quantum dots have shown great potential in bioimaging, targeted drug delivery, and cancer therapies. Biocompatibility, ease of synthesis, and ease of surface functionalization are among the significant properties of nonporous and mesoporous silica nanoparticles in various nanomedicine applications. Quantum dots due to their high brightness, long-lasting, wide and continuous absorption spectra, and high fluorescent quantum yield are being used as the new optical probes for bioassays. In addition about gold nanoparticles, the ease of preparation, stability, low cytotoxicity, and high extinction coefficient of light from visible to NIR regions are some properties that introduced them as important candidates in cancer drug and nanocarrier development. As a specific type of inorganic nanomaterials, magnetic nanoparticles that exhibit superparamagnetic are capable of being used as contrast agents in magnetic resonance imaging, site-specific gene and drug delivery, and diagnostic agents in the presence of an external magnetic field. This review will present the physicochemical properties of most popular inorganic nanoparticles and their recent applications in sensing and drug delivery.
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