Recent Advances in Ligand-Promoted Transition-Metal-Catalyzed Remote meta-C—H Functionalization of Arenes

Ligands can regulate both the steric and electronic effects of the catalytic center in transition-metal-catalyzed C-H activation reactions, leading to the site-selective C-H functionalization of arenes.In recent years, ligand-promoted remote C-H functionalization of arenes has developed rapidly.The recent progress on ligand-promoted transition-metal-catalyzed remote meta-selective C-H bond functionalization of arenes is summarized, and the limitations of the research field and prospects for future development are presented.