Association between the early use of antibiotics in infants born preterm and severe cerebral lesions and moderate-to-severe bronchopulmonary dysplasia

I read with interest the report by Letouzey et al describing the effects of early exposure to antibiotics in infants born very preterm at low risk for early-onset sepsis.1 They found no association between the early exposure to antibiotics with death, late-onset sepsis, and/or necrotizing enterocolitis. However, they reported an association with a greater risk of severe cerebral lesions and moderate-to-severe bronchopulmonary dysplasia.