The Chronic Fatigue Syndrome

Letters1 July 1995The Chronic Fatigue SyndromeKeiji Fukuda, MD, MPH, William C. Reeves, MD, and Stephen E. Strauss, MDKeiji Fukuda, MD, MPHCenters for Disease Control and Prevention; Atlanta, GA 30333National Institutes of Health; Bethesda, MD 20892Search for more papers by this author, William C. Reeves, MDCenters for Disease Control and Prevention; Atlanta, GA 30333National Institutes of Health; Bethesda, MD 20892Search for more papers by this author, and Stephen E. Strauss, MDCenters for Disease Control and Prevention; Atlanta, GA 30333National Institutes of Health; Bethesda, MD 20892Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-123-1-199507010-00019 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:The remarks from Dr. Rest, coauthor of the recent guidelines on chronic fatigue syndrome [1], bear careful reflection because they touch on important and complex issues that are easily misunderstood.The 1988 chronic fatigue syndrome working case definition [2] was revised to mitigate ambiguities and deficiencies that became apparent after field testing. The revised case definition remains a work in progress and not a “definitive” diagnostic tool. Thus, until an independent way to identify the syndrome is found, the validity of this or any similar case definition cannot be definitively established. Do these considerations negate the clinical value ...References1. Fukuda K, Straus SE, Hickie I, Sharpe MC, Dobbins JG, Komaroff A, and the International Chronic Fatigue Syndrome Study Group. The chronic fatigue syndrome: a comprehensive approach to its definition and study. Ann Intern Med. 1994; 121:953-9. Google Scholar2. Holmes GP, Kaplan JE, Gantz NM, Komaroff AL, Schonberger LB, Straus SE, et al. Chronic fatigue syndrome: a working case definition. Ann Intern Med. 1988; 108:387-9. Google Scholar Author, Article, and Disclosure InformationAffiliations: Centers for Disease Control and Prevention; Atlanta, GA 30333National Institutes of Health; Bethesda, MD 20892 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEicosapentaenoic acid-rich essential fatty acid supplementation in chronic fatigue syndrome associated with symptom remission and structural brain changesVoluntary motor function in patients with chronic fatigue syndromeLaborchemische, neurohormonelle und immunologische Befunde beim Fibromyalgie- und chronischen Müdigkeitssyndrom und ihre klinische RelevanzMitochondrial Dysfunction in Chronic Fatigue Syndrome 1 July 1995Volume 123, Issue 1Page: 74-76KeywordsBehaviorChronic fatigue syndromeDisabilitiesFatigueNauseaTouch ePublished: 15 August 2000 Issue Published: 1 July 1995 Copyright & PermissionsCopyright © 1995 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...