Meta-analysis of high-quality non-randomized studies comparing oncologic outcomes after minimally invasive compared with open radical hysterectomy for early-stage cervical cancer

Objective: Despite evidence from the Laparoscopy for Cervical Carcinoma (LACC) trial, there remains debate regarding the surgical approach for early-stage cervical cancer. We evaluate evidence from nonrandomized studies comparing overall and recurrence-free survival after minimally invasive versus open radical hysterectomy for early-stage cervical cancer.