医学
登革热
急性播散性脑脊髓炎
登革热病毒
脱髓鞘病
脑炎
脱髓鞘病
脑脊髓炎
儿科
疾病
白质脑病
病毒
病毒学
免疫学
多发性硬化
病理
作者
Mimi Ganguly,Prabhas Prasun Giri,Mausumi Mukherjee,Harshita Jagwani,Arundhati Banerjee
出处
期刊:Neurology India
[Medknow Publications]
日期:2022-01-01
卷期号:70 (3): 1244-1244
被引量:1
标识
DOI:10.4103/0028-3886.349659
摘要
Dengue is a common viral infection worldwide, though its neurological manifestations are infrequent (2%-11% in recent years) and can be varied as the Dengue virus per se is a non-neurotropic virus. Neurological manifestations of Dengue usually result from multisystem dysfunction which may be secondary to vascular leak or it can be due to direct virus invasion (dengue encephalitis) or an immunological phenomenon which is triggered by dengue infection (demyelinating disorders). Here we present two cases of dengue fever associated demyelinating disorders in two pediatric patients aptly depicting the two spectra of the disease. One of them is a case of fatal acute hemorrhagic leukoencephalopathy (AHLE) in a 3-year-old girl, that developed severe neurological sequelae while the other one is a case of an Acute disseminated Encephalomyelitis (ADEM) in a 3-year-old boy who had recovered with timely immunomodulatory therapy and appropriate management.
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