反式激活crRNA
清脆的
DNA
Cas9
生物
核糖核酸
计算生物学
核酸
遗传学
化学
核酸酶
基因
作者
Ines Fonfara,Hagen Richter,Majda Bratovič,Anaïs Le Rhun,Emmanuelle Charpentier
出处
期刊:Nature
[Springer Nature]
日期:2016-04-01
卷期号:532 (7600): 517-521
被引量:819
摘要
CRISPR-Cas systems that provide defence against mobile genetic elements in bacteria and archaea have evolved a variety of mechanisms to target and cleave RNA or DNA(1). The well-studied types I, II ...
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