医学
垂体机能减退
垂体卒中
亚临床感染
单中心
外科
回顾性队列研究
激素
垂体
儿科
内科学
垂体腺瘤
腺瘤
作者
Sandra Arbunea-Ghenoiu,Gheorghe Vasile Ciubotaru,Anda Dumitrașcu,Daniela Alexandrescu,Cristina Căpățînă,Cătălina Poiană
出处
期刊:Cureus
[Cureus, Inc.]
日期:2022-09-30
被引量:2
摘要
Background and objective Pituitary apoplexy (PA) is a possible life-threatening disorder due to spontaneous hemorrhage or impaired blood supply in the pituitary gland. It may present as an acute or subclinical form, and treatment options include either surgery or a conservative approach. The purpose of this study was to retrospectively analyze the clinical, imaging, and hormonal features, as well as the therapeutic outcomes, in a relatively short period of time in a series of consecutive patients with pituitary apoplexy (PA). Results Thirty-six patients were included, 50% presenting typical symptoms of PA. The presenting symptoms were headache (44.4%), visual abnormalities (44.4%), and digestive symptoms (22.2%). At diagnosis, hormonal deficiency was observed in 22 (61.1%) patients. Of the evaluated patients, 78.2% of the 23 operated cases and all unoperated cases presented tumor remnants. Vision improved in 81.8% of the operated and 100% of conservatively managed cases. Of all cases, 69.4% remained with long-term hypopituitarism. Conclusion Complex management of PA frequently leads to visual improvement but long-standing hypopituitarism.
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