Association between the degree of vertebrobasilar stenosis, location, infarction pattern, and QMRA flow state

医学 狭窄 椎动脉 冲程(发动机) 放射科 椎基底动脉供血不足 心脏病学 闭塞 磁共振成像 磁共振血管造影 内科学 机械工程 工程类
作者
Ahmad A. Ballout,Brendan Huang,Seok Yoon Oh,Karen Black,Panagiotis Sideras,Rohan Arora,Shadi Yaghi,Jeffrey M. Katz,Richard Libman
出处
期刊:Journal of Neuroimaging [Wiley]
卷期号:33 (4): 598-605
标识
DOI:10.1111/jon.13112
摘要

Abstract Background and Purpose We aimed to investigate the relationship between the degree and location of vertebrobasilar stenosis and quantitative magnetic resonance angiography (QMRA) distal flow. Methods We retrospectively reviewed patients who presented with acute ischemic stroke with ≥50% stenosis of the extracranial or intracranial vertebral or basilar arteries, and QMRA performed within 1 year of stroke. Standardized techniques were used to measure stenosis and to dichotomize vertebrobasilar distal flow status. Patients were grouped based on the involved artery and the severity of disease. All p ‐values were calculated using chi‐squared analysis and Fisher exact test with statistical significance defined as p < .05. Results Sixty‐nine patients met study inclusion, consisting of 31 with low distal flow and 38 with normal distal flow. The presence of severe stenosis or occlusion was 100% sensitive, but only 47% predictive and 26% specific of a low distal flow state. Bilateral vertebral disease was only 55% sensitive but was 71% predictive and 82% specific of a low‐flow state and was five times and nearly three times more likely to result in a low‐flow state compared to unilateral vertebral disease (14%) and isolated basilar disease (28%), respectively. Conclusions Severe stenosis of ≥70% may mark the minimal threshold required to cause hemodynamic insufficiency in the posterior circulation, but nearly half of these patients may remain hemodynamically sufficient. Bilateral vertebral stenosis resulted in a fivefold increase in QMRA low distal flow status compared to unilateral vertebral disease. These results may have implications in the design of future treatment trials of intracranial atherosclerotic disease.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
无花果应助GGZ采纳,获得10
刚刚
Hello应助豪豪采纳,获得10
2秒前
2秒前
2秒前
tidongzhiwu发布了新的文献求助10
3秒前
沉静立辉完成签到,获得积分10
3秒前
zzz发布了新的文献求助10
3秒前
忐忑的蛋糕完成签到,获得积分10
3秒前
花花发布了新的文献求助10
3秒前
可乐清欢完成签到,获得积分20
6秒前
7秒前
7秒前
7秒前
啦啦啦发布了新的文献求助10
7秒前
坚强幼晴发布了新的文献求助10
7秒前
昏睡的蟠桃应助lele采纳,获得50
8秒前
电化学小生完成签到,获得积分10
8秒前
王思甜发布了新的文献求助10
8秒前
9秒前
9秒前
9秒前
NexusExplorer应助魔幻幻桃采纳,获得10
10秒前
Kelly发布了新的文献求助10
10秒前
10秒前
CodeCraft应助小李子采纳,获得10
10秒前
小樱发布了新的文献求助10
11秒前
11秒前
11秒前
千纸鹤完成签到,获得积分10
11秒前
12秒前
12秒前
忐忑的鞅发布了新的文献求助10
12秒前
一颗药顽完成签到,获得积分10
13秒前
丘比特应助wenyh采纳,获得10
13秒前
正太低音炮完成签到,获得积分10
14秒前
14秒前
14秒前
ruby30完成签到,获得积分10
14秒前
15秒前
15秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Social Research Methods (4th Edition) by Maggie Walter (2019) 2390
A new approach to the extrapolation of accelerated life test data 1000
北师大毕业论文 基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 390
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
Robot-supported joining of reinforcement textiles with one-sided sewing heads 360
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4009871
求助须知:如何正确求助?哪些是违规求助? 3549812
关于积分的说明 11303839
捐赠科研通 3284342
什么是DOI,文献DOI怎么找? 1810591
邀请新用户注册赠送积分活动 886393
科研通“疑难数据库(出版商)”最低求助积分说明 811406