医学
眼压
夜行的
眼科
CLs上限
隐形眼镜
昼夜节律
气温日变化
低谷(经济学)
平均差
置信区间
内科学
宏观经济学
大气科学
经济
地质学
作者
Y. Zhang,Yifan Wei,Ching Hymn Christopher Lee,Ping Wai Or,I. K. Karunaratne,Mingjie Deng,Wenxin Yang,Iok Tong Chong,Yangfan Yang,Zidong Chen,Yanmei Fan,D.C.C. Lam,Minbin Yu
标识
DOI:10.1136/bjo-2023-323361
摘要
Aims To investigate the physiological nyctohemeral intraocular pressure (IOP) rhythms of normal Chinese adults using a novel contact lens sensor system (CLS) that can output IOP in millimetres of mercury (mm Hg) continuously. Methods Fifty-nine eyes of 59 normal Chinese adults completed 24-hour IOP monitoring using the novel CLS. A descriptive analysis was conducted on the 24-hour IOP mean, peak and acrophase, trough and bathyphase, fluctuation, and mean amplitude of intraocular pressure excursion (MAPE). The continuous data were analysed at several periods (diurnal period, 08:00–20:00 hours; nocturnal period, 22:00–06:00 hours; sleep time, 0:00–06:00 hours), and compared between right and left eyes, males and females, and different age ranges (<30, and ≥30), respectively. Results Normal adults had a lower peak, higher trough, smaller fluctuation and smaller MAPE (p<0.05 for all comparisons) but non-significantly different mean (p=0.695) in the nocturnal period or sleep time compared with the diurnal period. The 24-hour IOP peak and trough showed the frequency of occurrence ranging from 1.69% to 15.25% at an interval of 2 hours. No IOP parameter showed significant difference between right and left eyes (p>0.1 for all comparisons). The male group had larger 24-hour and diurnal IOP fluctuation and MAPE (p<0.05 for all comparisons). Subjects aged 30 or over had higher 24-hour and diurnal mean, higher peak, and larger MAPE (p<0.05 for all comparisons). Conclusion Continuous 24-hour IOP output from the CLS in normal Chinese was stable with a comparable mean level between day and night, as well as scattered acrophase and bathyphase. The 24-hour IOP mean increased with age, and IOP variations were positively correlated to age and male sex.
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