自愈水凝胶
生物分子
纳米技术
明胶
生物相容性材料
组织工程
化学
聚合物
材料科学
生物医学工程
高分子化学
有机化学
医学
作者
Fatima Ijaz,Hafiz Muhammad Tahir,Shaukat Ali,Aamir Ali,Hooria Ashraf Khan,Ayesha Muzamil,Hafiz Hamid Manzoor,Kunza Abdul Qayyum
标识
DOI:10.1016/j.ijbiomac.2023.127362
摘要
The need for biocompatible drug carriers has been significantly increased from the past few years. Researchers show great interest in the development of more versatile and sophisticated biomaterials based drug carriers. Hydrogels are beneficial drug carriers and easily release the controlled amount of drug at target site due to its tunable structure. The hydrogels made-up of potent biological macromolecules including collagen, gelatin, fibrin, elastin, fibroin, chitosan, starch, alginate, agarose and carrageenan have been proven as versatile biomaterials. These are three-dimensional polymeric networks, synthesized by crosslinking of hydrophilic polymers. The biological macromolecules based hydrogels containing therapeutic substances are used in a wide range of biomedical applications including wound healing, tissue engineering, cosmetics and contact lenses. However, many aspects related to hydrogels such as the mechanism of cross-linking and molecular entanglement are not clear. So, there is a need to do more research and exploration toward the extensive and cost-effective use of hydrogels. The present review article elaborately discusses the biomolecules based hydrogels and their possible biomedical applications in different fields.
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