Incidence of Heparin Resistance and Heparin Failure in Patients Receiving Extracorporeal Membrane Oxygenation – an Exploratory Retrospective Analysis

Unfractionated heparin (UFH) is used in most centers for extracorporeal membrane oxygenation (ECMO) anticoagulation. When standard doses do not achieve desired target values, heparin resistance is reported, most commonly defined as doses of UFH > 35 000 IU/d.