鼻咽癌
图像分割
人工智能
计算机科学
分割
变压器
医学
放射科
放射治疗
工程类
电压
电气工程
作者
Wanguo Zhao,Zhenxing Huang,Si Tang,Jichao Geng,Yunlong Gao,Yingying Hu,Wei Fan,Chuanli Cheng,Yongfeng Yang,Hairong Zheng,Dong Liang,Zixiang Chen
出处
期刊:IEEE Journal of Biomedical and Health Informatics
[Institute of Electrical and Electronics Engineers]
日期:2024-01-01
卷期号:: 1-12
标识
DOI:10.1109/jbhi.2024.3405993
摘要
Nasopharyngeal carcinoma (NPC) is a malignant tumor primarily treated by radiotherapy. Accurate delineation of the target tumor is essential for improving the effectiveness of radiotherapy. However, the segmentation performance of current models is unsatisfactory due to poor boundaries, large-scale tumor volume variation, and the labor-intensive nature of manual delineation for radiotherapy. In this paper, MMCA-Net, a novel segmentation network for NPC using PET/CT images that incorporates an innovative multimodal cross attention transformer (MCA-Transformer) and a modified U-Net architecture, is introduced to enhance modal fusion by leveraging cross-attention mechanisms between CT and PET data. Our method, tested against ten algorithms via fivefold cross-validation on samples from Sun Yat-sen University Cancer Center and the public HECKTOR dataset, consistently topped all four evaluation metrics with average Dice similarity coefficients of 0.815 and 0.7944, respectively. Furthermore, ablation experiments were conducted to demonstrate the superiority of our method over multiple baseline and variant techniques. The proposed method has promising potential for application in other tasks.
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