Fabrication, characterization of NiO–Co3O4/rGO based nanohybrid and application in the development of non-enzymatic glucose sensor

The current study is reporting the synthesis and characterization of NiO–Co3O4/rGO nanohybrid for nanocomposite for nonenzymatic glucose sensing. The prepared nanohybrids sample was characterized by X-rays diffraction (XRD), fourier transforms infrared spectroscopy (FTIR), and scanning electron microscopy (SEM). The XRD analysis exhibited the cubic crystalline phase for both NiO and Co3O4 in the binary composite. The vibrational mode of NiO and its nanohybrid with reduced graphene oxide (rGO) was defined using FTIR spectral analysis. SEM images of the nanoparticles depicted a non-spherical pattern randomly distributed throughout the whole matrix. The prepared sensor exhibited promising results for glucose sensitivity (345 μA mM) with a wide range of linear response from 1.23 × 10-4 mM to 10 mM and a low limit of detection of 0.13 μM. Further, the interference study was also performed using 100 µM fructose (FR), lactose (LA), uric acid (UA) and ascorbic acid (AA) and results exposed that these interfering species has not affected glucose determination. The obtained results suggested that the nanohybrid has enormous potential to act as a credible sensor for the determination of glucose.