纳米技术
毒性
纳米银
银纳米粒子
纳米-
纳米材料
材料科学
化学
纳米颗粒
复合材料
有机化学
作者
Jing Zhang,Fang Wang,Satya Siva Kishan Yalamarty,Nina Filipczak,Yi Jin,Xiang Li
摘要
Nano silver is one of the most widely used engineering nanomaterials with antimicrobial activity against bacteria, fungi, and viruses. However, the widespread application of nano silver preparations in daily life raises concerns about public health. Although several review articles have described the toxicity of nano silver to specific major organs, an updated comprehensive review that clearly and systematically outlines the harmful effects of nano silver is lacking. This review begins with the routes of exposure to nano silver and its distribution in vivo. The toxic reactions are then discussed on three levels, from the organ to the cellular and subcellular levels. This review also provides new insights on adjusting the toxicity of nano silver by changing their size and surface functionalization and their combination with other materials to form a composite formulation. Finally, future development, challenges, and research directions are discussed.
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