[Aims] The study is to confirm the control effect and security of 50% WG of nicosulfuron,mesotrione and fluroxypr-mepthyl against weeds in summer corn field.[Methods] Field trials were carried out by using methods of stems-leaves spraying and regular survey.[Results] The recommended dose of nicosulfuron,mesotrione and fluroxypr-mepthyl 50% WG was 97.5-195 g a.i./ha,and the integrated control effect reached 98.17% on weeds after 28 d.[Conclusions] Nicosulfuron,mesotrione and fluroxypr-mepthyl 50% WG shows good control to weeds in summer corn field and is safe on corn growth.