Risk factor for lung infection in recipients after liver transplantation: A meta‐analysis

医学 肝移植 内科学 优势比 置信区间 荟萃分析 纳入和排除标准 机械通风 肺移植 重症监护室 严格标准化平均差 风险因素 移植 肝病 病理 替代医学
作者
Jiaxue Zhang,Qiang He,Ling Du,Renyue Ji,Lingyue Yuan,Hongyang Zhang,Xinyu Yuan,Lifei Shen,Yingli Li
出处
期刊:Artificial Organs [Wiley]
卷期号:45 (3): 289-296 被引量:6
标识
DOI:10.1111/aor.13826
摘要

Lung infection (LI) often occurs in patients with liver transplantation (LT). This meta-analysis was conducted to determine the risk factors associated with LI after LT. We retrieved relevant research published as of February 2020 from eight electronic databases. The studies were reviewed against the inclusion and exclusion criteria. The Z test was used to determine the combined odds ratio (OR) or the standardized mean difference (SMD) of the risk factors. We used the OR and its corresponding 95% confidence interval (CI) or the SMD and its corresponding 95% CI to identify significant differences in risk factors. A total of nine studies were included, comprising a total of 1624 recipients. Six risk factors associated with LI were identified after LT: Model for end-stage liver disease score (MELD score) (SMD = 0.40), Child-Pugh class C (OR = 3.00), intensive care unit (ICU) hospital stay (SMD = 1.35), mechanical ventilation (SMD = 1.03), bilirubin (SMD = 0.39), and atelectasis (OR = 7.28). Although certain risk factors have been identified as important factors for LI after LT, which may provide a basis for clinical prevention, a well-designed prospective study should be conducted to validate the findings of this study.
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