热卡限制
锡尔图因
生物
西妥因1
卡路里
遗传学
基因
限制地点
细胞生物学
作者
Xiaolei Qiu,Katharine Brown,Yehu Moran,Danica Chen
标识
DOI:10.1016/j.bbapap.2009.09.015
摘要
The beneficial effects of calorie restriction diet in extending lifespan and preventing diseases have long been recognized. Recent genetic and molecular studies in model organisms began to uncover the molecular regulation of calorie restriction response, with the gene SIR2 playing an essential role. This article summarizes the latest development on how mammalian SIR2 homologs coordinately regulate the calorie restriction response.
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