We would like to briefly respond to some comments of Vivat and Twycross regarding our paper “Changing Practices in the Use of Continuous Sedation at the End of Life: A Systematic Review of the Literature”. 1 Heijltjes M. van Thiel G. Rietjens J. et al. Changing practices in the use of continuous sedation at the end of life. A systematic review of the literature. J Pain Symptom Manage. 2020; 60 (e3): 828-846 Abstract Full Text Full Text PDF PubMed Scopus (18) Google Scholar