Postnatal immune activation causes social deficits in a mouse model of tuberous sclerosis: Role of microglia and clinical implications.
神经炎症
生物
免疫学
炎症
巨噬细胞
作者
Manuel F. López-Aranda,Ishanu Chattopadhyay,Gayle M. Boxx,Elizabeth R. Fraley,Tawnie K. Silva,Miou Zhou,Miranda Phan,Isaiah Herrera,Sunrae Taloma,Rochelle Mandanas,Karen Bach,Michael J. Gandal,Daniel H. Geschwind,Genhong Cheng,Andrey Rzhetsky,Stephanie A. White,Alcino J. Silva
出处
期刊:Science Advances [American Association for the Advancement of Science] 日期:2021-09-17卷期号:7 (38)被引量:1
There is growing evidence that prenatal immune activation contributes to neuropsychiatric disorders. Here, we show that early postnatal immune activation resulted in profound impairments in social ...