体内
人性化鼠标
人肝
抗体
癌症研究
病毒学
免疫学
生物
体外
生物技术
生物化学
作者
Lander Foquet,Elizabeth M. Wilson,Lieven Verhoye,Markus Grompe,Geert Leroux‐Roels,John Bial,Philip Meuleman
出处
期刊：Methods in molecular biology
日期：2016-11-09
卷期号：: 117-130
被引量：18
标识
DOI：10.1007/978-1-4939-6506-9_8
摘要
Mice with humanized chimeric liver are promising in vivo tools to evaluate the efficacy of novel compounds or vaccine induced antibodies directed against pathogens that infect the human liver. In addition they can be used to study the human-type metabolism of medicinal compounds and hepatotoxicity.
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