Optical coherence tomography-based intraocular pressure monitoring principle

This paper presents the preliminary study on monitoring of intraocular pressure (IOP) of human eye by using optical coherence tomography (OCT). Because hypertension IOP can lead to Glaucoma, one of chronic diseases of the optic nerve, the periodic monitoring of IOP through tonometry is essential to prevent the Glaucoma. One of the most common tonometry methods to estimate IOP includes measuring corneal deflection by using either a direct contact or non-contact (e.g. air puff) impact force. However, this approach may be harmful to human eye. Therefore, it is necessary to develop the more reliable and safe monitoring method. In ophthalmology, the differentiation of open-angle glaucoma and normal eyes is used to monitor the IOP by using. Typically, peripapillary vessel density or superficial perifoveal macular vessel density measurements are currently utilized. In this study, optical OCT images of bovine eye was captured with different IOPs of bovine and analyzed to extract the signature where defines the relationship between IOP and optical OCT images.