A Broadly Applicable Method for Pd-Catalyzed Carboperfluoro-alkylation of Terminal and Internal Alkynes: A Convenient Route to Tri- and Tetrasubstituted Olefins

A three-component Pd-catalyzed difunctionalization of internal and terminal alkynes with iodoperfluoroalkanes and boronic acids is reported here. Under low catalyst loading and mild reaction conditions, perfluoroalkylated tri- and tetrasubstituted olefins were obtained in very good yields and in excellent regio- and stereoselectivities.