The convergence of artificial intelligence (AI) and nanotechnology has initiated a transformative journey, introducing innovative possibilities across various fields. This review article explores the dynamic interaction between these two disciplines, emphasizing their collaborative potential, notable accomplishments, and prevailing challenges. The integration of AI algorithms with nanotechnology has expedited material discovery, nanoscale characterization, personalized medical applications, and nano- electronics. AI's predictive capabilities have revolutionized the discovery of novel nanomaterials with customized properties, the enhancement of drug delivery systems, and the design of intricate nano-electronic components. However, this synergy is accompanied by challenges such as data quality, multidisciplinary cooperation, ethical considerations, and computational complexity. The fusion of AI and nanotechnology is poised to transform industries, unlock quantum advancements, and influence sustainable materials. As AI's capacities evolve, scholars are prepared to address challenges and harness the transformative potential of AI- nanotechnology integration.