前药
酰胺
分子
化学
结合
组合化学
构造(python库)
纳米技术
有机化学
材料科学
计算机科学
生物化学
数学分析
数学
程序设计语言
作者
Thomas Wharton,David R. Spring
标识
DOI:10.1002/chem.202404413
摘要
The ability to release a molecule from a larger construct in a controlled manner is of great importance to produce effective prodrugs, antibody‐drug conjugates, and chemical probes. Amides are ubiquitous functional groups and yet methods to utilise them as molecular release handles are seldom reported. This concept article highlights the advances made in amide release strategies and how these approaches have been utilised.
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