Carbon–Carbon Bond Formation Reactions Using Chiral Phase-Transfer Catalysts

The formation of carbon–carbon bonds in an enantioselective manner has been important in organic synthesis. Asymmetric phase-transfer catalysis for its formation has been recognized as a powerful and promising method for establishing practical synthetic reactions because of its advantages such as simplicity of operation, mild reaction conditions, suitability for large-scale synthesis, and environmental compatibility of the reaction system. Therefore, various asymmetric transformations have been developed in the past decade to synthesize optically pure and valuable organic compounds.