[Exploration and prospect of the whole course management model of osteoporosis].

Osteoporosis is a chronic progressive bone disease whose prevalence has increased significantly in China. Fragility fractures caused by osteoporosis pose a heavy burden on patients and their families. Therefore, early and efficient whole course management of osteoporosis is imperative. However, there are great challenges currently in the whole course management of osteoporosis, including lack of disease awareness, low rates of diagnosis and treatment, as well as poor patient compliance. As there is no consensus on the whole course management path to follow in clinical practice, this review analyzes the key points of whole course management of osteoporosis, such as the risk identification of fragility fracture, diagnosis and differential diagnosis, selection of initial treatment drugs, sequential or combined treatment and evaluation of treatment response etc. Based on the current management modes, including fracture liaison service, this review explores the whole course management path of osteoporosis which is suitable for China, including the whole course management ideas and implementation steps, establishing a platform to connect hospitals, communities, and families by application of information technology, developing an innovative system and mechanism indicates that the general practitioner will be responsible for clinical management and follow-up under instruction of clinical osteoporosis specialists, providing the community liaison service, organizing patient education activities such as bone health clubs, ultimately achieving a closed-loop communication among osteoporosis specialist, general practitioner, and patient, so that patients can benefit from it.骨质疏松症是一种中老年人群高发的慢性进展性骨病，其导致的脆性骨折给患者和家庭带来沉重的疾病负担，因此早期合理的骨质疏松症全程管理势在必行。但目前骨质疏松症的全程管理面临多种挑战，例如疾病知晓率低、诊治率低、患者依从性差等，临床实践也尚无共识性的全程管理路径可遵循。因此本文深入分析骨质疏松症全程管理要点，包括脆性骨折风险识别、骨质疏松症的诊断与鉴别、初始治疗药物选择、序贯或联合治疗以及治疗反应评估监测。从骨折联络服务与多学科联合管理模式等现况出发，探索适合中国国情的骨质疏松全程管理与路径。包括管理思路与实施步骤，建立基于医院、社区和患者的一体化信息平台；突出创新机制，使全科医生根据专科医生制订的个性化方案进行治疗、随访；建立社区联络员工作制度；组织骨健康俱乐部等患教活动，最终形成医院、社区、家庭闭环管理，使患者从中获益。.