Investigating the Involvement of the NLRP3/ASC/Caspase-1 and NF-κB/MAPK Pathways in the Pathogenesis of Gouty Arthritis: Insights from Irradiated and non-irradiated Trifolium alexandrium L. Extracts and Some Metabolites

Trifolium alexandrinum L. (TA), has traditionally been used in folk medicine for its anti-inflammatory properties against hyperuricemia and gout. However, the specific mechanisms of action of TA have not been thoroughly studied.