银屑病性关节炎
医学
银屑病
关节炎
炎性关节炎
皮肤病科
共病
乌斯特基努马
重症监护医学
内科学
类风湿性关节炎
阿达木单抗
作者
Francesco Caso,Mauro Fatica,Mario Ferraioli,Matteo Megna,Luca Potestio,Angelo Ruggiero,Nello Tommasino,Francesco Μaione,Raffaele Scarpa,Maria Sole Chimenti,Luisa Costa
标识
DOI:10.1080/14712598.2024.2384090
摘要
Psoriatic arthritis (PsA) is an immune-inflammatory disease that affects both joints, and entheses, and with diverse extra-articular manifestations (psoriasis, inflammatory bowel disease (IBD), and uveitis). A wide range of comorbid conditions, including cardiovascular diseases, obesity, metabolic syndrome (MetS), nonalcoholic fatty liver disease (NAFLD), mental health disorders (depression/anxiety), and osteoporosis are highly prevalent in course of PsA.Biological DMARDs (bDMARD), including TNF-inhibitors (TNFi), Interleukin (IL-17i) and IL-23i represent the cornerstone of the management of active disease. The use of these therapies obviously needs of considering comorbidities presence, safety aspects and contraindications.
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