化学
敌手
相（物质）
朊蛋白
色谱法
构象变化
生物物理学
立体化学
生物化学
有机化学
受体
医学
疾病
病理
生物
作者
Yangyi Liu,Marcus D. Tuttle,Mikhail A. Kostylev,Graham Roseman,Kurt W. Zilm,Stephen M. Strittmatter
摘要
Liquid-liquid phase separation (LLPS) of intrinsically disordered proteins has been associated with neurodegenerative diseases, although direct mechanisms are poorly defined. Here, we report on a maturation process for the cellular prion protein (PrP
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