失调
免疫学
炎症
肠道菌群
内科学
代谢物
医学
生理学
作者
Johannes Holle,Hendrik Bartolomaeus,Ulrike Löber,Felix Behrens,Theda Ulrike Patricia Bartolomaeus,Harithaa Anandakumar,Moritz I. Wimmer,Dai Long Vu,Mathias Kuhring,Ulrike Brüning,András Maifeld,Sabrina Geisberger,Stefan Kempa,Fabian Schumacher,Burkhard Kleuser,Philip Bufler,Uwe Querfeld,Stefanie Kitschke,Denise Engler,Leonard D. Kuhrt
出处
期刊：Journal of The American Society of Nephrology
日期：2022-08-19
卷期号：33 (12): 2259-2275
被引量：51
标识
DOI：10.1681/asn.2022030378
摘要
Gut barrier dysfunction and microbial metabolite imbalance apparently mediate the proinflammatory immune phenotype, thereby driving the susceptibility to cardiovascular disease. The data highlight the importance of the microbiota-immune axis in CKD, irrespective of confounding comorbidities.
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