痴呆
卷积神经网络
计算机科学
人工智能
预处理器
学习迁移
机器学习
深度学习
磁共振成像
疾病
模式识别(心理学)
医学
病理
放射科
作者
Muhammad Umair Ali,Kwang Su Kim,Majdi Khalid,Majed Farrash,Amad Zafar,Seung Won Lee
标识
DOI:10.3389/fpsyt.2024.1395563
摘要
This study addresses the pervasive and debilitating impact of Alzheimer’s disease (AD) on individuals and society, emphasizing the crucial need for timely diagnosis. We present a multistage convolutional neural network (CNN)-based framework for AD detection and sub-classification using brain magnetic resonance imaging (MRI). After preprocessing, a 26-layer CNN model was designed to differentiate between healthy individuals and patients with dementia. After detecting dementia, the 26-layer CNN model was reutilized using the concept of transfer learning to further subclassify dementia into mild, moderate, and severe dementia. Leveraging the frozen weights of the developed CNN on correlated medical images facilitated the transfer learning process for sub-classifying dementia classes. An online AD dataset is used to verify the performance of the proposed multistage CNN-based framework. The proposed approach yielded a noteworthy accuracy of 98.24% in identifying dementia classes, whereas it achieved 99.70% accuracy in dementia subclassification. Another dataset was used to further validate the proposed framework, resulting in 100% performance. Comparative evaluations against pre-trained models and the current literature were also conducted, highlighting the usefulness and superiority of the proposed framework and presenting it as a robust and effective AD detection and subclassification method.
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