New extraction techniques on bioseparations: 2. Pertraction, direct extraction

The second part of this review presents our original results on the separation of some biosynthetic products (antibiotics, carboxylic acids, alcohols) by pertraction and direct extraction from broths without biomass filtration. For the analyzed systems, the experimental conditions required for reaching maximum separation efficiency and the mathematical models describing the process have been established. For all the studied cases, these extraction techniques simplify the technologies and reduce the overall cost of the product.