Real-time affective dynamics surrounding everyday conflicts are central to the quality of relationships between mothers and their socioemotionally maturing adolescents. In this longitudinal study, we examined whether dyadic affective flexibility in early adolescence predicted trajectories of mother-adolescent relationship closeness and conflicts over time. We focused on flexibility not only in dyads' emotional fluctuations during conflict interactions (i.e., dynamic flexibility) but also in the repair of their affective patterns after conflict interactions (i.e., reactive flexibility). At Wave 1, 201 adolescents (11-12 years old, 46.3% girls) and mothers (87.5% Caucasian) completed two consecutive discussions about everyday conflicts and happy memories, respectively. Dynamic flexibility was derived from second-by-second affect coding via state space grids, and reactive flexibility was assessed as the latent change in dynamic flexibility across discussions. Annually for 5 years, including periods during the COVID-19 pandemic (i.e., Waves 3-5), mothers reported feelings of closeness with the adolescents, and both dyad members identified and rated the intensity of conflicts with each other. Results revealed that greater dynamic and reactive flexibility predicted greater and increasing closeness particularly from early to mid-adolescence. Greater dynamic and reactive flexibility were also associated with less intense and less diverse conflicts overall but not developmental changes in conflicts. These findings have implications beyond the immediate dyadic interactions around conflicts, suggesting that real-time flexibility within the mother-adolescent emotional system may serve as a resilience factor that buffers against the strains of relationship adjustment during adolescence at a longer timescale. (PsycInfo Database Record (c) 2025 APA, all rights reserved).