Voltammetric analysis of serotonin and epinephrine in the presence of guanine and adenine at Bismarck brown R amplified pencil graphite electrode

In present study, the novel sensing platform was electrochemically designed by incorporation of Bismarck brown R (BBR) as a enhancing substance onto the graphite pencil electrode(GPE) surface and successfully implemented for the electroanalysis of serotonin(SE) and epinephrine(EP) in assistant with adenine (AD) and guanine(GU) through cyclic and differential pulse voltammetric methods(CV and DPV). The morphology of electrode surface was characterised by scanning electron microscopy (SEM). The test solutions and operating conditions such as scan rate, varied supporting electrolyte pH and concentration of targeted analytes were optimised. The electrode kinetics of a tailored sensor was governed by both adsorption and diffusion phenomenon and gives a reduced detection limits for SE and EP respectively. The configured electrode proffers the potent and persistent specificity and sensibility followed by distinctly separated four anodic signals of SE, EP, AD and GU with appreciable increments in peak currents. Therefore, the offered sensor was cost effective, simple and applied in electrochemical monitoring and biosensing applications.