Agile scores are a good predictor of liver-related events in patients with NAFLD

We have read with great interest the recent paper by Sanyal et al., wherein they developed new FibroScan-based scores, Agile 4 and Agile 3+, to identify cirrhosis and advanced fibrosis (AF) (F≥3) in patients with non-alcoholic fatty liver disease (NAFLD), using several large international cohorts.1 Importantly, this new approach is primarily focused on reducing the proportion of patients with indeterminate results and improving the positive predictive value to rule-in cirrhosis or AF.