尿苷
细胞内
线粒体
糖酵解
细胞生物学
氧化应激
生物化学
氧化磷酸化
功能(生物学)
乙酰化
化学
新陈代谢
生物
核糖核酸
基因
作者
Xujing Bai,Ding Huang,Pan Xie,Ruiqiang Sun,Hang Zhou,Yu Liu
出处
期刊:PubMed
日期:2023-09-25
卷期号:39 (9): 3695-3709
标识
DOI:10.13345/j.cjb.220899
摘要
Uridine is one of the essential nutrients in organisms. To maintain normal cell growth and intracellular metabolism, the uridine must be maintained at certain concentration. Recent studies have shown that uridine can reduce inflammatory response in organisms, participate in glycolysis, and regulate intracellular protein modification, such as glycosylation and acetylation. Furthermore, it can protect cells from hypoxic injury by reducing intracellular oxidative stress, promoting high-energy compounds synthesis. Previous studies have shown that the protective effects of uridine are closely related to its effect on mitochondria. This review summarizes the effect of uridine on mitochondrial function.
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