伤口愈合
医学
细胞外基质
鼻粘膜
再生(生物学)
副鼻窦
病理
免疫系统
体内
外科
免疫学
细胞生物学
生物
生物技术
作者
Jean‐Baptiste Watelet,Claus Bachert,Philippe Gevaert,Paul Van Cauwenberge
出处
期刊:American Journal of Rhinology
[SAGE]
日期:2002-03-01
卷期号:16 (2): 77-84
被引量:111
标识
DOI:10.1177/194589240201600202
摘要
Background Wound healing is a highly coordinated process involving clot formation, inflammatory reaction, immune response, and, finally, tissue remodeling and maturation. Only few data regarding the specific healing of the nasal or sinusal mucosa are available. Methods After a short summary of the general principles of wound healing, the most important data regarding in vitro or in vivo models of wound healing of the nasal and paranasal mucosa are discussed. Attention is paid to clinical application. Main Findings First observations regarding the specific regulation of epithelial regeneration by growth factors have underlined the complex relationship between extracellular matrix and epithelium during the repair process. However, only poor and aspecific correlations can be described between endoscopically and histomorphologically defined postoperative phases.
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