Lv1
30 积分 2023-10-24 加入
Design, Synthesis, and Pharmacological Evaluation of Isoindoline Analogues as New HPK1 Inhibitors
1个月前
已完结
Development of an orally bioavailable CDK12/13 degrader and induction of synthetic lethality with AKT pathway inhibition
1个月前
已完结
Development of an orally bioavailable CDK12/13 degrader and induction of synthetic lethality with AKT pathway inhibition
1个月前
已完结
Discovery of Novel 2-Aminopyridine-Based and 2-Aminopyrimidine-Based Derivatives as Potent CDK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors and Hematological Malignancies
1个月前
已完结
Discovery of BAY-405: An Azaindole-Based MAP4K1 Inhibitor for the Enhancement of T-Cell Immunity against Cancer
1个月前
已完结
Synthetic Peptides with Genetic-Codon-Tailored Affinity for Assembling Tetraspanin CD81 at Cell Interfaces and Inhibiting Cancer Metastasis
3个月前
已完结
Sesquiterpene dimers with a rare skeleton from Chloranthus holostegius exhibiting multidrug resistance reversal activity in vitro and in vivo
3个月前
已完结
Discovery of D25, a Potent and Selective MNK Inhibitor for Sepsis Associated Acute Spleen Injury
3个月前
已完结
The First Discovery of Marine Polyoxygenated Cembranolides as Potential Agents for the Treatment of Ulcerative Colitis
3个月前
已完结
DHW-221, a dual PI3K/mTOR inhibitor, overcomes multidrug resistance by targeting P-glycoprotein (P-gp/ABCB1) and akt-mediated FOXO3a nuclear translocation in non-small cell lung cancer
4个月前
已完结
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