| 标题 |
 Optimization of Dissolved Oxygen Conditions for Corynebacterium glutamicum Producting L-arginine 谷氨酸棒杆菌产L-精氨酸溶氧条件的优化
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| 网址 | |
| DOI |
10.1016/j.biotechadv.2020.107118
doi
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| 其它 | In order to determine the most suitable dissolved oxygen concentration in the L-arginine fermentation process, the L-arginine production of Corynebacterium glutamicum ATCC14067-SG under different dissolved oxygen conditions was investigated by controlling the three dissolved oxygen levels of 5%, 20% and 35%. The reasons for the difference in arginine accumulation under different dissolved oxygen were studied by analyzing the growth and key metabolites. The results showed that under the condition of 5% dissolved oxygen, the accumulation of lactic acid, alanine, lysine, ornithine and glutamic acid were the highest. Under the condition of 35% dissolved oxygen, the accumulation of lactic acid, lysine and ornithine improved, but the accumulation of alanine and glutamic acid |
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