Discovery of sesquiterpenoids from the roots of Chloranthus henryi Hemsl. var. hupehensis (Pamp.) K. F. Wu and their anti-inflammatory activity by IKBα/NF-κB p65 signaling pathway suppression
化学
NF-κB
信号转导
生物化学
作者
Shuai Liu,Xiaoxia Wang,Juan Wu,Hui Yang,Zi-Mo Zhang,Peng‐Yu Zhuang,Huan Liu,Ke Du
Phytochemical analysis of Chloranthus henryi var. hupehensis roots led to the identification of a new eudesmane sesquiterpenoid dimer, 18 new sesquiterpenoids, and three known sesquiterpenoids. Among the isolates, 1 was a rare sesquiterpenoid dimer that is assembled by a unique oxygen bridge (C