癌症治疗
癌症
靶向治疗
癌症研究
癌症治疗
细胞毒性
医学
计算生物学
化学
生物
内科学
生物化学
体外
作者
Neil K. Taunk,Freddy E. Escorcia,Jason S. Lewis,Lisa Bodei
出处
期刊:The cancer journal
[Ovid Technologies (Wolters Kluwer)]
日期:2024-05-01
卷期号:30 (3): 218-223
标识
DOI:10.1097/ppo.0000000000000720
摘要
Abstract Radiopharmaceutical therapy has emerged as a promising approach for the treatment of various cancers. The exploration of novel targets such as tumor-specific antigens, overexpressed receptors, and intracellular biomolecules using antibodies, peptides, or small molecules has expanded the scope of radiopharmaceutical therapy, enabling precise and effective cancer treatment for an increasing number of tumor types. Alpha emitters, characterized by their high linear energy transfer and short path length, offer unique advantages in targeted therapy due to their potent cytotoxicity against cancer cells while sparing healthy tissues. This article reviews recent advancements in identifying novel targets for radiopharmaceutical therapy and applications in utilizing α-emitters for targeted treatment.
科研通智能强力驱动
Strongly Powered by AbleSci AI