磁刺激
背外侧前额叶皮质
医学
偏头痛
荟萃分析
前额叶皮质
神经科学
背外侧
物理医学与康复
刺激
心理学
内科学
精神科
认知
作者
Nabil Izzaatie Mohamad Safiai,Nur Afiqah Mohamad,Mohd Nizar Hamidon,Liyana Najwa Inche Mat,Fan Kee Hoo,Anna Misyail Abdul Rashid,Abdul Hanif Khan Yusof Khan,Wei Chao Loh,Janudin Baharin,Aaron Fernandez,Intan Nureslyna Samsudin,Mohd Hazmi Mohamed,Siew Mooi Ching,Kai Wei Lee,Vasudevan Ramachandran,Patricia Pozo‐Rosich,Wan Aliaa Wan Sulaiman
出处
期刊:Cephalalgia
[SAGE]
日期:2022-04-17
卷期号:42 (10): 1071-1085
被引量:5
标识
DOI:10.1177/03331024221092423
摘要
Objective To evaluate the efficacy of high-frequency repetitive transcranial magnetic stimulation over dorsolateral prefrontal cortex as a migraine prevention by conducting a systematic review and meta-analysis. Background The efficacy of high-frequency repetitive transcranial magnetic stimulation over dorsolateral prefrontal cortex as preventive migraine treatment remains debatable. Methods PubMed, Scopus, CINAHL, CENTRAL, and BioMed Central databases were searched from their inception until December 2020. Randomised trials comparing high-frequency repetitive transcranial magnetic stimulation over dorsolateral prefrontal cortex with sham for migraine prevention were included. The risk of bias was assessed using the Cochrane guidelines. Headache days, pain intensity, acute medication intake, and disability were extracted as study outcomes and the mean difference with a random-effects model was used to determine the effect size. Results Meta-analysis revealed that high-frequency repetitive transcranial magnetic stimulation over dorsolateral prefrontal cortex significantly reduced acute medication intake (Mean Difference = 9.78, p = 0.02, 95%CI: 1.60, 17.96, p = 0.02) and functional disability (Mean Difference = 8.00, p < 0.05, 95%CI: 4.21, 11.79). However, no differences were found in headache days and pain intensity reduction, although there was a slight trend favouring high-frequency repetitive transcranial magnetic stimulation. Conclusion High-frequency repetitive transcranial magnetic stimulation over dorsolateral prefrontal cortex may be effective in reducing acute medication intake and disability. However, more studies are needed to strengthen this preliminary evidence.
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