Design, synthesis, and characterization of a series of novel β-cyclodextrin functional monomers

In order to increase its solubility in water and improve β-cyclodextrin combination with guest molecules, chemical modification of β-cyclodextrin is a feasible and effective method. A variety of β-cyclodextrin derivatives are designed and introduced for pharmaceutical complexation and analytical chemistry application. In this study, a series of β-cyclodextrin derivatives containing unsaturated bonds is designed and synthesized. The products are characterized by MS, FTIR, 1 H NMR, and 13 C NMR. Some of the functional monomers may be used in the preparation of molecularly imprinted polymers, and preliminary studies have shown excellent molecular recognition ability. The prepared β-cyclodextrin functional monomers have potential application value in molecular recognition materials based on polymers.