银屑病
朗格汉斯细胞
医学
表皮(动物学)
细胞生物学
出处
期刊:Science
[American Association for the Advancement of Science (AAAS)]
日期:2018-03-16
卷期号:359 (6381): 1227-1229
标识
DOI:10.1126/science.359.6381.1227-t
摘要
Immunology
Psoriasis is an autoimmune skin condition that is linked to the proinflammatory cytokine interleukin-17 (IL-17), which is produced by T cells in the skin. Zheng et al. found that p38α signaling in skin-resident dendritic cells (Langerhans cells) was important for the pathogenesis of
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