化学
结直肠癌
癌症
癌症研究
计算生物学
生物化学
内科学
医学
生物
作者
Jinglin Zhang,Yixiang Lin,Jingyue Gao,Pan Yuan,Guihua Hou,Chun Guo,Feng Gao
标识
DOI:10.1016/j.bioorg.2024.107645
摘要
Colorectal cancer (CRC) is among the most lethal and prevalent malignancies in the world. Human epidermal growth factor receptor 2 (HER2) is a promising target for the diagnosis and treatment of CRC. In this study, we aimed to design, synthesize and label peptide-based positron emission tomography (PET) tracers targeting HER2-positive CRC, namely [
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