生物
遗传负荷
转座因子
拟南芥
遗传变异
人口
航程(航空)
拟南芥
换位(逻辑)
群体遗传学
遗传学
基因
基因组
突变体
近亲繁殖
哲学
社会学
人口学
复合材料
材料科学
语言学
作者
Juan Jiang,Yong‐Chao Xu,Zhiqin Zhang,Jia‐Fu Chen,Xiao‐Min Niu,Xing-Hui Hou,X. Li,Li Wang,Yong E. Zhang,Song Ge,Ya‐Long Guo
出处
期刊:The Plant Cell
[Oxford University Press]
日期:2023-11-30
卷期号:36 (4): 840-862
被引量:3
标识
DOI:10.1093/plcell/koad296
摘要
Abstract Genetic load refers to the accumulated and potentially life-threatening deleterious mutations in populations. Understanding the mechanisms underlying genetic load variation of transposable element (TE) insertion, a major large-effect mutation, during range expansion is an intriguing question in biology. Here, we used 1,115 global natural accessions of Arabidopsis (Arabidopsis thaliana) to study the driving forces of TE load variation during its range expansion. TE load increased with range expansion, especially in the recently established Yangtze River basin population. Effective population size, which explains 62.0% of the variance in TE load, high transposition rate, and selective sweeps contributed to TE accumulation in the expanded populations. We genetically mapped and identified multiple candidate causal genes and TEs, and revealed the genetic architecture of TE load variation. Overall, this study reveals the variation in TE genetic load during Arabidopsis expansion and highlights the causes of TE load variation from the perspectives of both population genetics and quantitative genetics.
科研通智能强力驱动
Strongly Powered by AbleSci AI