化学
离子液体
糠醛
噻唑
氧化物
石墨烯
硝基甲烷
组合化学
绿色化学
肉桂醛
有机化学
药物化学
催化作用
纳米技术
材料科学
作者
Maral Shekarchi,Farahnaz K. Behbahani
出处
期刊:Letters in Organic Chemistry
[Bentham Science]
日期:2021-03-01
卷期号:18 (4): 294-302
被引量:1
标识
DOI:10.2174/1570178617999200601170128
摘要
1-Butyl-3-methylimidazolium hydrogen sulfate [bmim]HSO<sub>4</sub> as a non-halogenated ionic liquid was loaded on graphene oxide ([bmim]HSO<sub>4</sub>/GO) and employed as a green, reusable, solid nanocatalyst for the preparation of polysubstituted pyrroles in the presence of amines (such as benzeneamine, 2-amino-4-methylthiazole, adenine (9H-purin-6-amine)), benzaldehydes or cinnamaldehyde or furfural, 1,3-dicarbonyl compounds, and nitromethane at 90-95°C. The advantages of this protocol are the synthesis of some novel polysubstituted pyrroles containing fluorine atoms, thiazole and adenine nuclei that are very important in pharmaceutical and drug discovery research in comparison to previously reported results.
科研通智能强力驱动
Strongly Powered by AbleSci AI