Clinical Utility of Contrast-enhanced Ultrasound for the Diagnosis of Lymphadenopathy

诊断优势比 医学 科克伦图书馆 诊断试验中的似然比 荟萃分析 接收机工作特性 优势比 曲线下面积 林地 放射科 超声造影 超声科 出版偏见 内科学
作者
Siyang Huang,Yunuo Zhao,Xian Jiang,Nan Lin,Mingxuan Zhang,Hang Wang,Aiping Zheng,Xuelei Ma
出处
期刊:Ultrasound in Medicine and Biology [Elsevier]
卷期号:47 (4): 869-879 被引量:9
标识
DOI:10.1016/j.ultrasmedbio.2020.12.020
摘要

This meta-analysis aimed to evaluate the diagnostic accuracy of contrast-enhanced ultrasonography (CEUS) in identifying lymphazdenopathy. PubMed, Web of Science, Embase and the Cochrane Library were searched for relevant articles through September 2020. A total of 16 articles, which included 1787 participants, were analyzed. The summary sensitivity, specificity, positive likelihood ratio (LR), negative LR and diagnostic odds ratio of CEUS for diagnosing lymphadenopathy were 0.88 (0.86–0.90), 0.90 (0.88–0.92), 6.04 (3.67–9.95), 0.15 (0.10–0.21) and 47.38 (23.45–95.66), respectively. The summary receiver operating characteristic (SROC) area under the curve (AUC) was 0.9405. After omitting outliers identified in a bivariate box plot and forest plot, heterogeneity was decreased, and the pooled sensitivity and specificity were 0.87 (0.84–0.90) and 0.87 (0.84–0.90), respectively. Furthermore, the SROC AUC was 0.9327. In conclusion, CEUS has the potential to be a valuable tool for characterizing lymphadenopathy and could provide clinical decision support. This meta-analysis aimed to evaluate the diagnostic accuracy of contrast-enhanced ultrasonography (CEUS) in identifying lymphazdenopathy. PubMed, Web of Science, Embase and the Cochrane Library were searched for relevant articles through September 2020. A total of 16 articles, which included 1787 participants, were analyzed. The summary sensitivity, specificity, positive likelihood ratio (LR), negative LR and diagnostic odds ratio of CEUS for diagnosing lymphadenopathy were 0.88 (0.86–0.90), 0.90 (0.88–0.92), 6.04 (3.67–9.95), 0.15 (0.10–0.21) and 47.38 (23.45–95.66), respectively. The summary receiver operating characteristic (SROC) area under the curve (AUC) was 0.9405. After omitting outliers identified in a bivariate box plot and forest plot, heterogeneity was decreased, and the pooled sensitivity and specificity were 0.87 (0.84–0.90) and 0.87 (0.84–0.90), respectively. Furthermore, the SROC AUC was 0.9327. In conclusion, CEUS has the potential to be a valuable tool for characterizing lymphadenopathy and could provide clinical decision support.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
马小柯完成签到,获得积分20
刚刚
whitebird完成签到,获得积分10
刚刚
1秒前
西米露完成签到 ,获得积分10
2秒前
科目三应助ExtroGod采纳,获得10
2秒前
跳跃毒娘发布了新的文献求助10
3秒前
stuffmatter应助ataybabdallah采纳,获得10
3秒前
满姣发布了新的文献求助10
4秒前
925完成签到,获得积分10
4秒前
4秒前
4秒前
4秒前
Tiliar完成签到,获得积分10
6秒前
ddt完成签到,获得积分10
6秒前
lalala关注了科研通微信公众号
6秒前
Estrella应助科研通管家采纳,获得10
7秒前
Akim应助科研通管家采纳,获得10
7秒前
7秒前
7秒前
852应助科研通管家采纳,获得10
7秒前
CipherSage应助乔心采纳,获得10
7秒前
传奇3应助南方姑娘采纳,获得10
7秒前
8秒前
落尘完成签到,获得积分10
8秒前
欢呼的鸣凤应助易拉罐采纳,获得10
9秒前
Voloid发布了新的文献求助10
9秒前
星辰大海应助l2023采纳,获得10
9秒前
qing_he完成签到,获得积分10
10秒前
10秒前
小小泽完成签到,获得积分10
10秒前
cc20231022完成签到,获得积分10
12秒前
linger发布了新的文献求助10
12秒前
Xiaoxin_Ju完成签到,获得积分10
13秒前
老实冰薇完成签到,获得积分10
13秒前
优雅的琳完成签到,获得积分10
13秒前
14秒前
房LY完成签到,获得积分10
14秒前
Janson完成签到,获得积分10
14秒前
在水一方应助蓝色毛衣采纳,获得30
15秒前
15秒前
高分求助中
Evolution 10000
Sustainability in Tides Chemistry 2800
The Young builders of New china : the visit of the delegation of the WFDY to the Chinese People's Republic 1000
юрские динозавры восточного забайкалья 800
English Wealden Fossils 700
Foreign Policy of the French Second Empire: A Bibliography 500
Chen Hansheng: China’s Last Romantic Revolutionary 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3147102
求助须知:如何正确求助?哪些是违规求助? 2798398
关于积分的说明 7828848
捐赠科研通 2455058
什么是DOI,文献DOI怎么找? 1306576
科研通“疑难数据库(出版商)”最低求助积分说明 627831
版权声明 601565