亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

Detection of microplastics in human lung tissue using μFTIR spectroscopy

微塑料 傅里叶变换红外光谱 人肺 人口 聚对苯二甲酸乙二醇酯 呼吸系统 化学 医学 内科学 色谱法 环境化学 材料科学 物理 复合材料 环境卫生 量子力学
作者
Lauren C. Jenner,Jeanette M. Rotchell,Robert T. Bennett,Michael E. Cowen,Vasileios Tentzeris,Laura R. Sadofsky
出处
期刊:Science of The Total Environment [Elsevier BV]
卷期号:831: 154907-154907 被引量:873
标识
DOI:10.1016/j.scitotenv.2022.154907
摘要

Airborne microplastics (MPs) have been sampled globally, and their concentration is known to increase in areas of high human population and activity, especially indoors. Respiratory symptoms and disease following exposure to occupational levels of MPs within industry settings have also been reported. It remains to be seen whether MPs from the environment can be inhaled, deposited and accumulated within the human lungs. This study analysed digested human lung tissue samples (n = 13) using μFTIR spectroscopy (size limitation of 3 μm) to detect and characterise any MPs present. In total, 39 MPs were identified within 11 of the 13 lung tissue samples with an average of 1.42 ± 1.50 MP/g of tissue (expressed as 0.69 ± 0.84 MP/g after background subtraction adjustments). The MP levels within tissue samples were significantly higher than those identified within combined procedural/laboratory blanks (n = 9 MPs, with a mean ± SD of 0.53 ± 1.07, p = 0.001). Of the MPs detected, 12 polymer types were identified with polypropylene, PP (23%), polyethylene terephthalate, PET (18%) and resin (15%) the most abundant. MPs (unadjusted) were identified within all regions of the lung categorised as upper (0.80 ± 0.96 MP/g), middle/lingular (0.41 ± 0.37 MP/g), and with significantly higher levels detected in the lower (3.12 ± 1.30 MP/g) region compared with the upper (p = 0.026) and mid (p = 0.038) lung regions. After subtracting blanks, these levels became 0.23 ± 0.28, 0.33 ± 0.37 and 1.65 ± 0.88 MP/g respectively. The study demonstrates the highest level of contamination control and reports unadjusted values alongside different contamination adjustment techniques. These results support inhalation as a route of exposure for environmental MPs, and this characterisation of types and levels can now inform realistic conditions for laboratory exposure experiments, with the aim of determining health impacts.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
12秒前
量子星尘发布了新的文献求助10
12秒前
longh发布了新的文献求助20
14秒前
cc发布了新的文献求助10
16秒前
aa发布了新的文献求助10
17秒前
lucky完成签到 ,获得积分10
18秒前
123完成签到,获得积分10
27秒前
28秒前
28秒前
fat完成签到,获得积分10
31秒前
123发布了新的文献求助10
32秒前
脑洞疼应助lf采纳,获得10
43秒前
健壮的花瓣完成签到 ,获得积分10
46秒前
oywt发布了新的文献求助10
54秒前
霸气鞯完成签到 ,获得积分10
55秒前
55秒前
lf发布了新的文献求助10
58秒前
58秒前
59秒前
1分钟前
bbdd2334发布了新的文献求助10
1分钟前
1分钟前
1分钟前
李健的小迷弟应助bbdd2334采纳,获得10
1分钟前
1分钟前
忧伤的风华完成签到,获得积分10
1分钟前
thanhvader999完成签到,获得积分10
1分钟前
小乘号子发布了新的文献求助10
1分钟前
量子星尘发布了新的文献求助10
1分钟前
1分钟前
小马甲应助科研通管家采纳,获得10
1分钟前
1分钟前
科研通AI2S应助科研通管家采纳,获得10
1分钟前
1分钟前
轻松的惜芹应助白日梦采纳,获得20
1分钟前
1分钟前
悦耳的沛岚完成签到,获得积分10
1分钟前
1分钟前
Xiaowen发布了新的文献求助10
1分钟前
123发布了新的文献求助10
1分钟前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 700
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3976600
求助须知:如何正确求助?哪些是违规求助? 3520700
关于积分的说明 11204482
捐赠科研通 3257320
什么是DOI,文献DOI怎么找? 1798683
邀请新用户注册赠送积分活动 877881
科研通“疑难数据库(出版商)”最低求助积分说明 806613